We study neuroscience at the intersections of:
sleep, metabolism, stress, and sedation
Examples of questions that drive our science:
- How does the brain link energy expenditure, body temperature regulation, and sleep?
- How does stress lead to disruptions in sleep?
- What neural pathways link sleep disturbances to metabolic changes?
- How are the circuits regulating sleep involved in generating aspects of anesthetic states?
- How does sleep disruptions impact our ability to cope with stressors?
- How does the brain link energy expenditure, body temperature regulation, and sleep?
Current Projects:
- Preoptic hypothalamic circuits that regulate metabolism
- Supramammilary nucleus in stress and arousal
- Torpor induction for neural protection after ischemic stroke
Techniques:
- Fiber Photometry
- Optogenetics
- Chemogenetics
- Behavior
- Microscopy
- EEG
- Indirect calorimetry
- Thermal imaging
- Viral tools
- Fiber photometry
